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trifarotene
Modality
small molecule
Mechanism
12.1 Mechanism of Action Trifarotene is an agonist of retinoic acid receptors (RAR), with particular activity at the gamma subtype of RAR. Stimulation of RAR results in modulation of target genes which are associated with various processes, including cell differentiation and mediation of inflammation. The exact process by which trifarotene ameliorates acne is unknown.
Targets
Retinoic acid receptor gamma, Retinoic acid receptor beta, Retinoic acid receptor alpha
Storage
—
Approved
acne vulgaris — FDA
In trial
acne vulgaris
Source
Last verified
2026-04-19
lib/moa-data.ts for the shape; add an entry keyed by trifarotene.