Modality
small molecule (oral)
Mechanism
PDE4 inhibitor
Targets
PDE4
Storage
room temperature
Approved
plaque psoriasis — FDA 2014 · psoriatic arthritis — FDA 2014 · Behçet oral ulcers — FDA 2019
In trial
—
Monitoring
weight, depression screen
Last verified
2026-04-14
Mechanism of action
Otezla label (FDA, 2024)drugtargetsignalingeffectorcellularphenotype⊣ red bar = blocked/reduced by drug