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roflumilast (topical)

Zoryve

Modality
small molecule (topical)
Mechanism
PDE4 inhibitor
Targets
PDE4
Storage
room temperature
Approved
plaque psoriasis — FDA 2022 · seborrheic dermatitis — FDA 2023 · atopic dermatitis — FDA 2024
In trial
Sources
Last verified
2026-04-14
No curated MOA diagram yet. See lib/moa-data.ts for the shape; add an entry keyed by roflumilast (topical).