ketoconazole

Modality

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Mechanism

Mode of Action In vitro studies suggest that ketoconazole impairs the synthesis of ergosterol, which is a vital component of fungal cell membranes. It is postulated that the therapeutic effect of ketoconazole in seborrheic dermatitis is due to the reduction of M. ovale, but this has not been proven.

Targets

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Storage

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Approved

seborrheic dermatitis — FDA

In trial

seborrheic dermatitis

Sources

DailyMed (FDA label)ClinicalTrials.gov

Last verified

2026-04-23

No curated MOA diagram yet. See lib/moa-data.ts for the shape; add an entry keyed by ketoconazole.

Formulations

2% cream1% / 2% shampoo