ciclopirox

Modality

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Mechanism

Mechanism of Action Ciclopirox is a hydroxypyridone antifungal agent although the relevance of this property for the indication of seborrheic dermatitis is not known. Ciclopirox acts by chelation of polyvalent cations (Fe 3+ or Al 3+ ), resulting in the inhibition of the metal-dependent enzymes that are responsible for the degradation of peroxides within the fungal cell.

Targets

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Storage

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Approved

seborrheic dermatitis — FDA

In trial

seborrheic dermatitis

Sources

DailyMed (FDA label)ClinicalTrials.gov

Last verified

2026-04-23

No curated MOA diagram yet. See lib/moa-data.ts for the shape; add an entry keyed by ciclopirox.

Formulations

0.77% cream / gel / suspension1% / 1.5% shampoo