calcipotriene

Modality

small molecule

Mechanism

12.1 Mechanism of Action Calcipotriene is a synthetic vitamin D3 analog that has a similar receptor binding affinity as natural vitamin D3. However, the exact mechanism of action contributing to the clinical efficacy in the treatment of psoriasis is unknown.

Targets

—

Storage

—

Approved

psoriasis — FDA

In trial

atopic dermatitis, psoriasis, acne vulgaris

Sources

DailyMed (FDA label)ClinicalTrials.gov

Last verified

2026-06-14

No curated MOA diagram yet. See lib/moa-data.ts for the shape; add an entry keyed by calcipotriene.

Formulations

0.005% cream0.005% ointment0.005% solution (scalp)0.005% foam